Recombinant Enzymes
Pbserum recombinant enzymes are the result of years of biotechnological research by specialized biologists, biochemists, and engineers in our laboratories based in Albacete, Spain.
Seeking to boost the regenerative power of enzymes, our group of expert scientists developed the unique technology of Pbserum, which has transformed the way various skin diseases and disorders are managed in clinical practice all over the world.
Being a true revolution in global medicine, Pbserum has opened countless therapeutic possibilities to doctors, specialists, and of course, to patients.
Biotechnological active principles that act in synergy with recombinant enzymes:
o Vitamin A
Works in synergy with keratinase to reduce hyperkeratosis and promote cell renewal. Reduces the excessive production of sebum which is responsible for acne breakouts. Stimulates the production of endogenous collagen and helps to maintain correct moisture levels in the dermis.
o Vitamin B complex
The complex of vitamins B1, B3, B5, and B6 act on the different problems associated with oily skin, thanks to its sebum-regulating, anti-inflammatory and skin-barrier repairing action. Minimizes the appearance of pores and comedones and revitalizes the skin.
o Vitamin C
A powerful antioxidant that prevents and delays the cellular aging process. Stimulates the production of collagen in the skin, improving its firmness and inhibiting melanin production, reducing the appearance of spots and providing luminosity to the skin. It also helps treat small inflammatory processes.
o Vitamin E
Lipophilic antioxidant that neutralizes free radicals caused by UV radiation and other external agents. Stimulates cell growth in the dermis and increases water retention at the cellular level.
o DMAE
It is a natural antioxidant with an immediate lifting effect. Improves the tone and the elasticity of the skin, reducing expression lines.
o Hyaluronic acid
Low molecular weight hyaluronic acid can penetrate the deep layers of the skin. Fills in wrinkles, fine lines and improves cell cohesion, by inhibiting trans epidermal water loss.



Technology
Pbserum enzymes are of bacterial origin and were developed through a complex biotechnological process exclusive to Pbserum. A key factor is the use of genetic DNA recombination technology, known as recombinant technology, to obtain enzymes synthesized by bacterial microorganisms, yet have the same structure and sequence as the human enzyme. Thanks to this, procedures based on recombinant enzymes offer a low level of immunogenicity, allowing a safe, effective, pure, and biological treatment.
Lyophilization is a dehydration method of the active ingredients by rapid freezing and subsequent sublimation of the ice formed under reduced pressure conditions. A product of high purity and safety is then obtained.
This method achieves high stability of the active principles, reserving 100% of the enzymes ’and vitamins’ activity and properties while avoiding the need to use preservatives and additives.
Microemulsions are oily solutions that are obtained by the union of two immiscible liquids with a very small-sized particle. This stabilizes enzymes in microcapsules to improve their penetration efficiently and safely. Additionally, the texture of this type of formulation facilitates massaging, without leaving residues and helps to obtain optimal results.
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Efficacy
pbserum’s recombinant enzymes base their efficacy on their high specificity and substrate selectivity, as well as on the important role they play in tissue regeneration mechanisms. Through pbserum enzymes, we have managed to enhance this regenerative function and thereby improve the condition of one of the most complex organs that contributes the most to general health: the skin.
Using the appropriate recombinant enzyme or the ideal combination of enzymes, as well as the correct therapeutic application, it is possible to reduce skin damage in an accelerated way, including aging signs (wrinkles, expression lines, flaccidity, hyperpigmentation), blemishes, sequelae of acne, scars, fibrosis, cellulite and localized fat, among others.

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Source: https://pbserum.com/enzymes/recombinant-enzymes/